Opteron 6380 's Advantages
Lower TDP (115W vs 300W)
Xeon w5 3535X 's Advantages
Released 11 years and 9 months late
Higher specification of memory (4800 vs 1866)
Newer PCIe version (5 vs 2)
Higher base frequency (2.9GHz vs 2.5GHz)
Larger L3 cache size (52.5MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)