Opteron 8212 HE (F3) 's Advantages
Lower TDP (68W vs 250W)
Intel Xeon Platinum 9221 's Advantages
Released 12 years and 8 months late
Higher specification of memory (2933 vs 667)
Newer PCIe version (3 vs 1)
Higher base frequency (2.1GHz vs 2GHz)
More modern manufacturing process (14nm vs 90nm)