Opteron 8216 HE (F2) 's Advantages
Lower TDP (68W vs 120W)
AMD EPYC 4484PX 's Advantages
Released 17 years and 9 months late
Higher specification of memory (5200 vs 667)
Newer PCIe version (5 vs 1)
Higher base frequency (4.4GHz vs 2.4GHz)
More modern manufacturing process (5nm vs 90nm)