Opteron 8216 HE (F2) 's Advantages
Lower TDP (68W vs 320W)
AMD EPYC 9274F 's Advantages
Released 16 years and 3 months late
Higher specification of memory (4800 vs 667)
Newer PCIe version (5 vs 1)
Higher base frequency (4.05GHz vs 2.4GHz)
More modern manufacturing process (5nm vs 90nm)