Opteron 8216 HE (F2) 's Advantages
Higher base frequency (2.4GHz vs 2.2GHz)
Lower TDP (68W vs 330W)
Xeon 6780E 's Advantages
Released 17 years and 10 months late
Higher specification of memory (6400 vs 667)
Newer PCIe version (5 vs 1)
More modern manufacturing process (5nm vs 90nm)