Opteron 8216 HE (F2) 's Advantages
Lower TDP (68W vs 80W)
Xeon E 2456 's Advantages
Released 17 years and 4 months late
Higher specification of memory (4800 vs 667)
Newer PCIe version (5 vs 1)
Higher base frequency (3.3GHz vs 2.4GHz)
More modern manufacturing process (10nm vs 90nm)