Opteron 8218 (F2) 's Advantages
Higher base frequency (2.6GHz vs 2.4GHz)
Lower TDP (95W vs 130W)
AMD EPYC 7303 's Advantages
Released 17 years and 1 months late
Higher specification of memory (3200 vs 667)
Newer PCIe version (4 vs 1)
More modern manufacturing process (7nm vs 90nm)