Xeon E6540 's Advantages
Lower TDP (105W vs 225W)
AMD EPYC 7643 's Advantages
Released 11 years late
Higher specification of memory (3200 vs 1333)
Newer PCIe version (4 vs 2)
Higher base frequency (2.3GHz vs 2GHz)
Larger L3 cache size (256MB vs 18MB)
More modern manufacturing process (7nm vs 45nm)