Xeon E7 4820 's Advantages
Lower TDP (105W vs 270W)
Intel Xeon Gold 6454S 's Advantages
Released 11 years and 9 months late
Higher specification of memory (4800 vs 1333)
Higher base frequency (2.2GHz vs 2GHz)
Larger L3 cache size (60MB vs 18MB)
More modern manufacturing process (10nm vs 32nm)