AMD Radeon R9 280 's Advantages
Lower TDP (200W vs 345W)
AMD Radeon RX Vega 64 Liquid Cooling 's Advantages
Released 3 years and 5 months late
Boost Clock has increased by 80% (1677MHz vs 933MHz)
More VRAM (8GB vs 3GB)
Larger VRAM bandwidth (483.8GB/s vs 240.0GB/s)
2304 additional rendering cores