AMD Radeon R9 280X 's Advantages
More VRAM (3GB vs 2GB)
Larger VRAM bandwidth (288.0GB/s vs 64.00GB/s)
1280 additional rendering cores
AMD Radeon PRO W6300 's Advantages
Released 8 years and 3 months late
Boost Clock has increased by 104% (2040MHz vs 1000MHz)
Lower TDP (25W vs 250W)