AMD Radeon R9 280X 's Advantages
More VRAM (3GB vs 2GB)
Larger VRAM bandwidth (288.0GB/s vs 48.00GB/s)
1536 additional rendering cores
AMD Radeon Pro WX 2100 's Advantages
Released 3 years and 8 months late
Boost Clock has increased by 22% (1219MHz vs 1000MHz)
Lower TDP (35W vs 250W)