AMD EPYC 7453 's Advantages
Released 14 years and 1 months late
Higher specification of memory (3200 vs 667)
Newer PCIe version (4 vs 1)
More modern manufacturing process (7nm vs 90nm)
Opteron 8220 's Advantages
Higher base frequency (2.8GHz vs 2.75GHz)
Lower TDP (95W vs 225W)