AMD EPYC 7643 's Advantages
Released 14 years and 7 months late
Higher specification of memory (3200 vs 667)
Newer PCIe version (4 vs 1)
More modern manufacturing process (7nm vs 90nm)
Opteron 8218 (F3) 's Advantages
Higher base frequency (2.6GHz vs 2.3GHz)
Lower TDP (95W vs 225W)