AMD EPYC 7643 's Advantages
Released 11 years and 6 months late
Higher specification of memory (3200 vs 1333)
Newer PCIe version (4 vs 2)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (7nm vs 45nm)
Xeon X3450 's Advantages
Higher base frequency (2.667GHz vs 2.3GHz)
Lower TDP (95W vs 225W)