AMD EPYC 7663 's Advantages
Released 13 years and 7 months late
Higher specification of memory (DDR4-3200 vs DDR2)
Newer PCIe version (4 vs 1)
More modern manufacturing process (7nm vs 90nm)
Opteron 2222 's Advantages
Higher base frequency (3GHz vs 2GHz)
Lower TDP (95W vs 240W)