Intel Xeon E5 2680 's Advantages
Larger L3 cache size (20MB vs 16MB)
Intel Xeon E 2378G 's Advantages
Released 9 years and 6 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 3)
Higher base frequency (2.8GHz vs 2.7GHz)
More modern manufacturing process (14nm vs 32nm)
Lower TDP (80W vs 130W)