Opteron 2216 (F3) 's Advantages
Higher base frequency (2.4GHz vs 1.9GHz)
Lower TDP (95W vs 350W)
Intel Xeon w9 3495X 's Advantages
Released 16 years and 6 months late
Higher specification of memory (4800 vs 2)
Newer PCIe version (5 vs 1)
More modern manufacturing process (10nm vs 90nm)