Opteron 2216 (F3) 's Advantages
Higher base frequency (2.4GHz vs 2GHz)
Lower TDP (95W vs 385W)
Xeon w9 3595X 's Advantages
Released 18 years late
Higher specification of memory (4800 vs 2)
Newer PCIe version (5 vs 1)
More modern manufacturing process (10nm vs 90nm)