Opteron 2220 SE (F2) 's Advantages
Higher base frequency (2.8GHz vs 2GHz)
Lower TDP (119W vs 500W)
Xeon 6980P 's Advantages
Released 18 years and 1 months late
Higher specification of memory (8800 vs 2)
Newer PCIe version (5 vs 1)
More modern manufacturing process (5nm vs 90nm)