Opteron 3350 HE 's Advantages
Higher base frequency (2.8GHz vs 2.1GHz)
Lower TDP (45W vs 390W)
AMD EPYC 9845 's Advantages
Released 11 years and 10 months late
Higher specification of memory (6000 vs 3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (320MB vs 8MB)
More modern manufacturing process (3nm vs 32nm)