Opteron 3380 's Advantages
Higher base frequency (2.6GHz vs 2.1GHz)
Lower TDP (65W vs 270W)
Intel Xeon Gold 6538N 's Advantages
Released 11 years late
Higher specification of memory (5200 vs 3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (60MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)