Opteron 6278 's Advantages
Higher base frequency (2.4GHz vs 2GHz)
Lower TDP (115W vs 120W)
AMD EPYC 8224PN 's Advantages
Released 11 years and 4 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (64MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)