Opteron 6278 's Advantages
Released 5 years and 1 months late
Newer PCIe version (2 vs 1)
More modern manufacturing process (32nm vs 90nm)
Lower TDP (115W vs 120W)
Opteron 8222 SE 's Advantages
Higher specification of memory (667 vs 3)
Higher base frequency (3GHz vs 2.4GHz)