Xeon E5540 's Advantages
Higher base frequency (2.533GHz vs 2.2GHz)
Lower TDP (80W vs 330W)
Xeon 6780E 's Advantages
Released 15 years and 3 months late
Higher specification of memory (6400 vs 1066)
Newer PCIe version (5 vs 2)
Larger L3 cache size (108MB vs 8MB)
More modern manufacturing process (5nm vs 45nm)