Xeon E7 4860 's Advantages
Higher specification of memory (1333 vs 3)
Larger L3 cache size (24MB vs 15MB)
Intel Xeon E5 2643 v2 's Advantages
Released 2 years and 5 months late
Higher base frequency (3.5GHz vs 2.266GHz)
More modern manufacturing process (22nm vs 32nm)