AMD Radeon R9 M290X 's Advantages
More VRAM (4GB vs 2GB)
Larger VRAM bandwidth (153.6GB/s vs 64.00GB/s)
512 additional rendering cores
AMD Radeon Pro W6300M 's Advantages
Released 8 years late
Boost Clock has increased by 127% (2040MHz vs 900MHz)
Lower TDP (25W vs 100W)