Opteron 6386 SE 's Advantages
Higher base frequency (2.8GHz vs 2.4GHz)
Lower TDP (140W vs 360W)
AMD EPYC 9654 's Advantages
Released 10 years late
Higher specification of memory (4800 vs 1600)
Newer PCIe version (5 vs 2)
Larger L3 cache size (384MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)